Low-Calorie, High-Protein Ketogenic Diet Versus Low-Calorie, Low-Sodium, and High-Potassium Mediterranean Diet in Overweight Patients and Patients with Obesity with High-Normal Blood Pressure or Grade I Hypertension: The Keto–Salt Pilot Study

AbstractDietary interventions are the first-line treatment for overweight individuals (OW) and individuals with obesity (OB) who have high-normal blood pressure (BP) or grade I hypertension, particularly when they are at low-to-moderate cardiovascular risk (CVR). However, current guidelines do not specify the most effective dietary approach for optimising cardiovascular and metabolic outcomes in this population.This study aimed to compare the effects of a low-calorie, high-protein ketogenic diet (KD) versus a low-calorie, low-sodium, and high-potassium Mediterranean diet (MD) on BP profiles assessed via ambulatory BP monitoring (ABPM). It also evaluated changes in anthropometric measures, metabolic biomarkers, and body composition measured by bioelectrical...